Trends in Clinical and Medical Sciences

Correlation between diabetes mellitus and thyroid dysfunction

S. Srinivas
Department of Medicine, Geethanjali Medical college, Udaipur, Rajasthan, India.; drsrinivas.1111@ gmail.com

Abstract

Aim: To assess relation between diabetes mellitus and thyroid dysfunction.
Methodology: 105 type II diabetes mellitus patients of both genders were included. Serum TSH (Thyroid Stimulating Hormone), free \(T_3\) (Triiodothyronine) and free \(T_4\)(Thyroxine) were determined in all enrolled patients.
Results: There were 50 males and 55 females in the present study. Age group 21-30 years had 15 patients, 31-40 years had 26, and 41-50 years had 64 patients. Duration of diabetes was 8.4 years, and the level of glycosylated hemoglobin (HbA1C) was 9.2 years. A significant difference was observed (P< 0.05). Serum T3 was increased by 15% and decreased by 4%. Free T3 was increased in 5% and decreased in 13%, and free T4 was increased in 7% and decreased in 5%. There were 20 hypothyroidism and 29 hyperthyroidism patients. Maximum hypothyroidism patients (12) and hyperthyroidism patients (14) were seen with >7 HbA1C levels.
Conclusion: Most of the type II DM patients had hypothyroidism than hyperthyroidism.

Keywords:

Diabetes; Thyroid dysfunction; Thyroxine.