Trends in Clinical and Medical Sciences

Cardiological manifestations of Hypothyroidism in ECG and ECHO-a hospital based cross sectional study

Rajeswari R\(^{1}\), Sreegeetha Ravilla\(^{2}\), Ravikant\(^{3}\) and Arun N\(^{4,*}\)
\(^{1}\) Department of Medicine and Neurology, SK Hospital Trivandrum, Medipulse Hospital, Jodhpur, India.
\(^{2}\) Department of General Medicine, Katuri Medical College, Guntur, Andhra Pradesh, India.
\(^{3}\) Department of Medicine and Gastroenterology, INHS Kalyani Vishakapatnam, India.
\(^{4}\) Department of General Medicine, Military Hospital, Trivandrum, Kerala 695006, India.
Correspondence should be addressed to Arun N at jazziyer@gmail.com

Abstract

Background: Hypothyroidism manifests itself in a wide range of clinical manifestations. ECG and ECHO changes have been reported among patients with both subclinical and manifest hypothyroidism.
Objectives: To enumerate the cardiological manifestations of hypothyroidism in ECG and ECHO.
Methods: The study was carried out as a cross-sectional study comprising 50 patients aged 18 years and above, of both sexes who were detected to have hypothyroidism. A convenient non-random sampling technique was used to select study participants from all eligible patients in the study population. The diagnosis of hypothyroidism was confirmed by measuring serum TSH, total T3 and T4, and subsequently, patients underwent ECG and echocardiography. A p-value <0.05 was considered statistically significant.
Results: It was observed that the majority of the study patients belonged to the middle age group and were females. Overt hypothyroidism was noted in 78%, and low levels of T3 and T4 were observed in 64% and 78%, respectively. Most of the study patients had elevated triglyceride levels (96%), while ECG and ECHO abnormalities were detected in 30%. Low voltage complex was the most commonly noted ECG abnormality (8%), and left ventricular diastolic dysfunction (LVDD) was the most common ECHO abnormality (18%).
Conclusions: ECG and ECHO changes are observed in a considerable proportion of patients with hypothyroidism, with low voltage complexes and LVDD being the most common, respectively.

Keywords:

Cardiological manifestations; ECG; ECHO; Hypothyroidism.