Trends in Clinical and Medical Sciences

A study of clinico-pathological relation of adenovirus associated with respiratory infections in children

Dr. Shabarna Roy\(^{1}\), Dr.Shibani Pal\(^{2}\), Dr. Suvomoy Karan\(^{3}\) and Dr. Shreya Dutta\(^{4,*}\)
\(^{1}\) Associate Professor, Department of Pediatrics, R.G. Kar Medical College, Kolkata, West Bengal, India.
\(^{2}\) RMO, Department of Pediatrics, R.G. Kar Medical College, Kolkata, West Bengal, India.
\(^{3}\) Senior Resident, Department of Pediatrics, R.G. Kar Medical College, Kolkata, West Bengal, India.
\(^{4}\) Junior Resident, Department of Pediatrics, R.G. Kar Medical College, Kolkata, West Bengal, India.
Correspondence should be addressed to Dr. Shreya Dutta at shibanicmc@gmail.com

Abstract

Introduction: Adenoviruses are DNA viruses responsible for varieties of human diseases that affect the gastrointestinal tract, respiratory tract, and eye. There are seven species of adenoviruses categorized from A to G with two subgroups. The classification correlates with clinical presentation, antigenic character, and epidemiological spread and can be identified by the genetic methods.
Aims: To study the clinico-pathological relation of adenovirus associated with respiratory infections in children.
Material and Methods: Department of Pediatrics, R.G.Kar Medical College, Kolkata.
Results: In the present study, this was performed by two steps molecular techniques. The first was by the determination of adenovirus by the use of PCR for fiber gene with common primers for adenovirus. The PCR was confirmed to be positive in 11 samples. The differences in the determination of adenovirus in respiratory infections can be attributed to the difference of the studied population.
Conclusion: The prevalence of adenovirus with respiratory tract infections mainly in pneumonia with genotypes 3 and 7 as the predominant geno types in those in children.

Keywords:

Adenovirus; Predominant geno types; PCR; DNA; Respiratory tract infections and pneumonia.