Introduction: Fever with thrombocytopenia is a common clinical presentation among patients in tertiary care hospitals. Various etiologies, such as malaria, dengue, leptospirosis, typhoid, miliary tuberculosis, and septicemia, are the common causes of fever with thrombocytopenia.
Aim: This study aimed to determine the various etiologies of febrile illness in children with thrombocytopenia, study their bleeding and clinical manifestations, and examine their correlation with the severity of platelet count.
Materials and methods: This study included 1000 pediatric patients with thrombocytopenia between January 2021 and December 2021 at an autonomous state medical college in Firozabad, Uttar Pradesh.
Results: In our study, the most common etiology was dengue, followed by sepsis and hematological malignancies. The most common age group of patients was 10-15 years. The severity of cases was determined based on the grading of thrombocytopenia and bleeding and clinical manifestations. Fever and myalgia were the most common clinical presentations of patients with thrombocytopenia.
Conclusion: Platelet count is a good predictor of bleeding manifestations due to severe thrombocytopenia, which can lead to life-threatening conditions. Prompt diagnosis is crucial to start treatment as soon as possible, including platelet transfusions for patients.
