An experimental study conducted by Ankit Kumar and colleagues (Kumar, Gupta, Pandey, Govil, and Patel, “Status of Arsenic Contamination in District Lakhimpur, Uttar Pradesh, India,” in Emerging Trends in Science, Social Science and Engineering, edited by Aggarwal, Pandey, Naik, Mishra, Raj, Tripathi, and Shukla, pp. 60-73, ISBN 9789358380125, Astitva Prakashan, Bilaspur, Chhattisgarh) has identified significant levels of arsenic contamination in the groundwater of Lakhimpur district, Uttar Pradesh. Their findings indicate that arsenic levels are notably higher in the shallow regions compared to the deeper India Mark II regions across eight selected study sites. Building on these findings, this paper aims to apply a dose-response Hill model to analyze and explain the observed patterns of arsenic contamination in the groundwater resources of Lakhimpur district.