Poultry farms in Ghana are experiencing a decline, and some are at risk of collapsing due to the high cost of poultry feed. The aim of this paper is to assist poultry farmers in increasing their profits by reducing the cost of poultry feed. The linear programming technique is implemented to utilize locally available feed ingredients to formulate layer feed mix for the various stages of poultry growth, which includes chick mash (starter), grower, and prelayer. Mathematical models are constructed based on the nutrient requirements of the layers, nutrient composition of the available ingredients, and any other restrictions on the available ingredients for the formulation. Seven decision variables and eleven constraints are identified. Compared to the existing practice, it is estimated that the LP model’s optimal solution can reduce feed formulation costs by approximately 30%, 19%, and 14% in chick mash, grower, and prelayer, respectively.