Aim: To assess risk factors for development of type II diabetes. Materials & Methods: 80 patients of type 2 diabetes mellitus >40 years of age were put in group 1 group 2 were healthy subjects irrespective of gender. Factors such as family history, physical activity, blood pressure, alcohol consumption and BMI was recorded. Results: Alcohol consumption was present in 45 in group 1 and 20 un group 2, family history was positive in 65 group 1 and 12 in group 2, sedentary life was seen in 52 group 1 and 25 in group 2, BMI was underweight seen in 14 in group 1 and 5 in group 2, normal 12 in group 1 and 46 in group 2, overweight 30 BMI was underweight seen in 14 in group 1 and 5 in group 2, normal12 in group 1 and 14 in group 2 and obese 22 and 15 46 in group 2. Blood pressure was normal seen 16 in group 1 and 42 in group 2, pre- hypertension 24 in group 1 and 26 in group 2, hypertension stage 1 in 30 in group 1 and 10 in group 2 and hypertension stage 2 seen in 10 in group 1 and 2 in group 2. A significant difference was observed (P< 0.05). Conclusion: Common risk factors in diabetes was overweight, hypertension, lack of physical activity and alcohol consumption.
Aim: To evaluate anesthetic management in renal transplant patients. Methodology: Ninety- two renal transplant patients were part of the study. Parameters such as type of transplant, reason for chronic kidney disease, preoperative data, history of dialysis, preoperative anesthesia management, monitoring details and the outcome were recorded. Results: Chronic glomerulonephritis (CGN) in 28 (30.4%), chronic interstitial nephritis (CIN) in 20 (21.7%), polycystic kidney disease (PCKD) in 11 (11.9%), obstructive nephropathy (Ob. N) in 4 (4.3%), diabetic nephropathy (DN) in 8 (8.7%), hereditary nephropathy in 3 (3.2%), reflux nephropathy in 12 (13%) and membranoproliferative glomerulonephritis (MPGN) in 6 (6.5%). In 32 (35.6%) patients, isoflurane was inhalational agent and recovery time was 25.1 minute, in 40 (43.4%), desflurane was inhalational agent and recovery time was 22.7 minutes and in 20 (21.7%), sevoflurane was inhalational agent and recovery time was 32.1 minutes. A significant difference was observed (P< 0.05). Conclusion: Anesthesia management has made renal transplantation safe and predictable. Postoperative maintenance of renal transplant patients have contributed to the success of renal transplant programme.
Aim: To compare tension band wire and circumferential wiring for patellar fractures. Materials & Methods: One hundred twenty adult patients in age ranged 18- 50 years of either gender was randomly divided into groups viz. group 1 treated with tension band wire and group 2 with circumferential wiring for patellar fractures. Reich and Rosenberg scale, rage of motion and complications were recorded in both groups and compared. Results: At 4 weeks in group 1 and group 2, restriction of last \(10^{0}- 20^{0}\) was seen in 24 and 27, restriction of \(20^0-50^0\) was seen in 14 and 13, restriction \(>50^0\) was observed in 22 and 20. At 8 weeks, no restriction was seen in 8 and 9, restriction of last \(10^0- 20^0\) was seen in 38 and 39, restriction of \(20^0-50^0\) was seen in 10 and 9, restriction >500 was seen in 4 and 3. At 12 weeks, no restriction was seen in 15 and 20, restriction of last \(10^0- 20^0\) was seen in 35 and 32, restriction of \(20^0-50^0\) was seen in 8 and 7 and restriction \(>50^0\) was seen in 2 and 1 in group 1 and 2 patients respectively. A significant difference was observed (P< 0.05). Conclusion: Both techniques for the management of patellar fractures were equally effective in achieving functional outcome.
This paper aims to compare 0.1% topical triamcinolone acetonide, oral methotrexate, and a combination of 0.1% topical triamcinolone acetonide and oral methotrexate in the management of oral lichen planus. 60 histologically confirmed cases of oral lichen planus were divided into 3 groups. Group T was given 0.1% topical triamcinolone acetonide, group M was given topical methotrexate and group C was given combination of both 0.1% topical triamcinolone acetonide and oral methotrexate. Clinical severity score and VAS was compared. The mean CSS at baseline was 5.4 in group T, 4.2 in group M and 4.1 in group C and at 4 months was 2.6 in group T, 2.1 in group M and 0.82 in group C. Baseline VAS was 6.5 in group T, 6.2 in group M and 7.1 in group C and at 4 months was 2.5 in group T, 1.3 in group M and 0.25 in group C. Group T had 3.2 years, group M had 3.1 years and group C had 3.3 years of duration of symptoms. It is concluded that the combination of triamcinolone and methotrexate exhibited maximum relieve of symptoms in patients with oral lichen planus.
The aim of this paper is to assess Serum Adenosine Deaminase (ADA), Erythrocyte Sedimentation Rate (ESR) and C-Reactive Protein (CRP) levels in patients with Psoriasis. Sixty- four patients with psoriasis were divided into three groups (mild, moderate, and severe) based on PASI scores. PASI score <10 defined psoriasis as mild, between 10 and 20 as moderate, and >20 as severe. The hsCRP was assayed by an enzyme-linked immunosorbent assay BIOS kit. ADA was measured through kinetic method. ESR was calculated using Westergren method. Group I patients had 8 males (mild), 9 males (moderate) and 10 males (severe) and group II had 20 males. There were 12 females (mild), 14 females (moderate) and 11 females (severe) and group II had 30 females. A non- significant difference was observed (P> 0.05). The mean hSCRP level in group I patients was 54.2 ng/ml and in group II was 19.6 ng/ml. The mean ADA level in group I patients was 22.5 U/L and in group II was 8.1 U/L. The mean ESR was 28.4 mm/h in group I and 13.2 mm/h in group II. A significant difference was observed (P< 0.05). This study demonstrated higher hSCRP, ESR and ADA level among patients suffering from psoriasis compared to healthy control.
The aim of this paper is to diagnose pre-eclampsia with spot urine albumin-creatinine ratio (ACR). Our study comprised of one hundred ten pregnancies within 20-28 weeks of gestation. Spot mid- stream urine sample was collected from all pregnant females and urine ACR estimation was done using immunoturbidimetric microalbumin method and modified Jaffe’s method for creatinine estimation. We found sensitivity of 90.4%, specificity of 98%, PPV of 91.6% and NPV of 97.2%. Systolic blood pressure in unaffected subjects was 110.2 mm Hg and in pre- eclamplsia was 152.6 mm Hg. Diastolic blood pressure in unaffected subjects was 78.4 mm Hg and in pre- eclamplsia was 96.8 mm Hg. In unaffected subjects, 4.5% showed positive test and 95.5% showed negative test. In pre- eclampsia subjects, 87.2% showed positive test and 12.8% showed negative test. Mann Whitney U test showed significant difference between two (Significant, P< 0.05). It has been observed that the role of urine albumin creatinine ratio in detection of Pre-eclampsia is evident. A higher sensitivity and specificity revealed its usefulness in early detection.
Aim: To assess various risk factors for development of CHD among patients. \Methodology: Seventy- eight patients of either sex were included. Various parameters such as age, gender, cardiac markers, family history, history of alcohol intake and smoking was recorded. Results: There were 32 patients >45 years of age and 46 below 45 years of age. Out of 78 patients, females were 27 and males were 51. It was found that 26 had primary education, 37 had secondary and 15 had higher education. 38 were employed and 40 were non- employed. 42 were married and 36 were unmarried. Family history was positive in 51 and negative in 26. 20 had hypertension, 36 had CHD and 22 had both HTN & CHD. 45 had habit of smoking, 47 had alcoholism and 40 had no physical activity. A significant difference was observed (P< 0.05). Conclusion: Common risk factors for CHD was obesity, hyperglycaemia, family history, high LDL- C, ALT level, smoking, alcoholism and lack of physical activity.
Aim: To study 82 cases of nasal polyposis undergoing functional endoscopic sinus surgery (FESS). Methodology: Our study comprised of 82 patients presenting with the symptoms of nasal polyposis (38 male patient, 44 female patients). All managed with FESS. Parameters assessed were NOSE score and nasal endoscopy score pre- operatively which was compared with post- operative score at 6 months and 12 months. Results: We found pre- operative NOSE score was \(65.2\pm 5.7,\) at 6 months was \(28.4\pm 4.1\) and at 12 months post- operatively was \(24.2\pm 3.6.\) We found pre- operative nasal endoscopic score was 6.02, 6 months score was 3.1 and 12 months score was 2.5. Conclusion: Patients nasal endoscopy score and NOSE symptom score was improved after treatment. Functional endoscopic sinus surgery is treatment of choice in patients with chronic rhinosinusitis with nasal polyps.
Aim: To calculate size, shape and position of mental foramen. Materials & Methods: 50 dry human mandibles of either gender (20- females, 30- males) were included. The position of mental foramen in horizontally was calculated based on classification proposed by Bokhari. The vertical position was divided into six types using the modified Ngeow and Yuzawati criteria. Size was measured both vertically and horizontally with the help of vernier caliper and expressed as mean. Results: Most common horizontal position was II seen in both males (left- 56%, right- 50%) and females (left- 60%, right- 58%). Most common vertical position was 2 seen in males (left- 62%, right- 65%) and females (left- 55%, right- 52%). Most common shape was oval seen in both genders (males- 68% left, 62% right) and (females- 70% left, 72% right). A significant difference was observed \((P<0.05)\). Conclusion: Variation in shape, size and position was observed both males and females, however, most common shape found to be oval and position was II horizontally and 2 vertically in both genders.
