Background and Aim: Due to the etiological agent, Salmonella enterica serovar typhi (S.Typhi), enteric fever is a potentially lethal multisystemic disease. Leukopenia is considered a key feature of Enteric fever, but studies have shown it to be present in only 20-25% of cases. The aim of the present study was to determine specific hematological changes in typhoid fever.
Material and Methods: There were 300 individuals overall, who had typhoid fever clinical diagnosis. 150 patients were chosen as the case group and 150 as the control group out of the total. Blood samples were taken and analysed in a medical hospital for various haematological parameters as well as the Widal test in 300 patients with clinical suspicion of typhoid fever.
Results: In around one-third of cases, anorexia and abdominal pain were also observed. The least common symptoms were headache and diarrhoea. In patients who tested positive for typhoid, anaemia was present in 32% of cases, leukocytosis predominated over leukopenia, and thrombocytopenia affected roughly 24% of cases, which was significantly higher than the control group’s rate.
Conclusion: Our research led us to the conclusion that men get typhoid fever more frequently than women. And this can be explained by the fact that male subjects exhibit higher levels of the predisposing factors that lead to typhoid fever; this is likely due to their occupational and social practises, which tend to give male subjects greater immunity to this infection than do female subjects. Typhoid fever also tends to infect those who are uneducated and of poor socioeconomic position. Significant haematological alterations occur in people with typhoid fever.
