ISSN: XXXX-XXXX (Online) XXXX-XXXX (Print)

Evaluation of microbial profile and antimicrobial susceptibility pattern of CSOM patients

Author(s): Dr. Sachin Parmar1, Dr Surendra Kumar Mahore2, Dr. Priyesh Marskole3, Dr. Ramesh Agrawal4, Dr Rashmi Randa5, Dr. Rajendra Kumar Mahore6
1Assistant Professor, Department of Community Medicine, NSC Government Medical College, Khandwa, M.P.
2Demonstrator, Department of Microbiology, Bundelkhand Medical College, Sagar, M.P.
3Associate Professor, Department of Community Medicine, NSC Government Medical College, Khandwa, M.P.
4Assistant Professor, Department of Microbiology, NSC Government Medical College, Khandwa, M.P.
5Associate Professor, Department of Pediatric, Gandhi Medical College, Bhopal, M.P.
6Demonstrator, Department of Community Medicine, Gandhi Medical College, Bhopal, M.P.
Copyright © Dr. Sachin Parmar, Dr Surendra Kumar Mahore, Dr. Priyesh Marskole, Dr. Ramesh Agrawal, Dr Rashmi Randa, Dr. Rajendra Kumar Mahore. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Background: Chronic suppurative otitis media (CSOM) is the commonest clinical condition diagnosed in ENT out patients department (OPD) in the developing country like: India. CSOM can lead to serious intracranial/extracranial complications. Hence knowledge of local bacteriological pattern and its antibiotic sensitivity may help for treating them with appropriate antibiotic therapy.
Methods: This prospective study was done with the collaboration of ENT and microbiology department. in a tertiary care centre, India The pus sample was collected from clinically suspected CSOM patients and culture sensitivity as done. Identification of bacterial isolates and antibiotic susceptibility patter was done by standard CLSI guidelines.
Results: On assessing about 122 patients of CSOM, most of them (2 group with male predominance. The commonest organism isolated was Pseudomonas species (24.2%) followed by klebsiella. Pseudomonas species was most sensitive to imipenem, colistin and polymixin b Staphylococcus aureus was mainly sensitive to linezolid and Vancomycin.
Conclusion: The study concludes imipenem for Pseudomonas species and linezolid and Vancomycin for Staphylococcus was most sensitive drug. The appropriate and adequate antibiotic therapy is always recommended for chronic otitis media to avoid complications.

Keywords: Chronic suppurative otitis media; Microbial profile; Antibiotic susceptibility; Pseudomonas aeruginosa; Staphylococcus aureus.