ISSN: XXXX-XXXX (Online) XXXX-XXXX (Print)

Study of prevalence of cytomegalovirus in male partner of infertile couple and its impact on seminal analysis in a tertiary care hospital of Kolkata

Author(s): Sagar Das1, Bosumita Sinha1
1Department Of Physiology, R.G. Kar Medical College, Kolkata.
Copyright © Sagar Das, Bosumita Sinha. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

Abstract

Introduction: Cytomegalovirus (CMV), a double-stranded DNA virus belongs to a family called herpesviridae or human herpesviruses (HHVs). CMV is spread by direct contact with infectious body fluids such as nasal secretions, saliva, tears, urine, genital secretion or breast milk. After contamination, the virus initially replicates in the epithelial cells at the site of entry, followed by hematogenous spread to numerous organs and cell types.
Aims: to estimate prevalence of CMV in a population of male partners of infertile couples attending a tertiary care hospital of Kolkata and also to determine the impact of CMV infection on sperm parameters.
Materials and method: The proposed study is an observational and descriptive study of cross-sectional study was conducted in department of Physiology, R.G. Kar Medical College & Hospital, Kolkata. The study period was One year January 2021 – January 2022. 56 patients were included in this study.
Result: We showed that, lower number of patients had Normal Morphology in with Cytomegalovirus [4 (100.0%)] this was not statistically significant (p=0.6895). Association of Addiction with Cytomegalovirus was statistically significant (p=0.0059) and Infertility DX with Cytomegalovirus was not statistically significant (p=0.6088). It was found that, higher number of patients had Height in without Needed Mechanical Ventilation [29 (65.9%)] compared to with Needed Mechanical Ventilation [4 (44.4%)] It was not statistically significant (p=0.0504).
Conclusion: we concluded that cytomegalovirus was associated with in male partner of infertile couple and its impact on seminal analysis a tertiary care hospital.

Keywords: Cytomegalovirus (CMV);, Infertile couples; Sperm parameters.