Ptolemy Journal of Chemistry (PJC)

In this work we have described the synthesis of Zinc Oxide nanoparticles through chemical and biological methods. For biological synthesis Aspargillus niger was used. The product obtained was characterized through different analytical techniques like XRD, SEM and EDX. The obtained results were matched with the literature. It was confirmed that the Zinc Oxide nanoparticles can also be prepared from Aspargillus niger.Which may be more ecofriendly and economical compared to other commonly used methods.

Topological indices are numerical numbers associated with a graph that helps to predict many properties of underlined graph. In this paper we aim to compute multiplicative topological indices of Circulant graph.

The objective of the present work was to develop and validate of an analytical method for the quantitative determination of Fexo. HCL and Pseudo. HCL in a combine tablet dosage form by \(UV-V\) is spectrophotometry and TLC. The main problem was to separate the two active ingredient from a single bilayered tablet because both the A.P.I’s were soluble in the same solvents. As media selection, distilled water and ethanol \((1:1)\) were used for Pseudo. HCl and methanol for Fexo. HCl, in which both the drugs were soluble and stable for a sufficient time. Both drugs were measured at \(220\)nm and \(247\)nm, where they showed maximum absorbance. Beer Lambert’s law was obeyed at concentration range \(4-14\) ppm and \(5-30\) ppm for Fexo. HCL and Pseudo HCL respectively. Fexo. HCl \((Y=0.0643x+0.9370)\) was measured with correlation coefficient \(r =0.9574\) and Pseudo. HCl \((Y=0.0843x+0.0219)\) with correlation coefficient \(r =0.9992\). The results of analysis have been validated statistically and recovery studies were carried out as \(99.29\%\pm 0.943\) and \(99.29\%\pm 0.941\) which were close to the assay value \(100.1\% \& 100.6 \%\). Precision of the method was measured which showed results for SD \((99.57 \% \;\;\& \;\;99. 51% )\) and \(\%\) RSD \((99.53 \%\;\; \&\;\; 99.54)\). The proposed method may be suitably applied for the analysis of Fexo. HCL and Pseudo.HCL in tablet pharmaceutical formulation for routine analysis.