Open Journal of Mathematical Sciences (OMS)

Several neurodegenerative diseases such as Alzheimer’s Disease (AD), Huntington’s Disease (HD), Parkinson’s Disease (PD), and Amyotrophic Lateral Sclerosis (ALS) as well as ischemic strokes all show signs of excess oxidative stress due to increased production of reactive oxygen species (ROS). The author here posits here that ascorbic acid (AA), commonly known as Vitamin C, can help prevent such neurodegenerative disorders. The author proposes a mathematical model that captures the biochemical dynamics between AA, dehydroascorbic acid (DHA), and ROS in the brain and performs simulations under control and neurodegenerative disease situations. Then, a variety of treatments using AA and DHA were proposed and simulated to examine their efficacy.

A numerical study has been carried out in the analysis of two dimensional, incompressible and steady convective flow over a stretching surface in the presence of chemical reaction along with viscous dissipation. A mathematical model which resembles the physical flow problem has been developed. Similarity transformations are used to convert the fundamental partial differential equations into a system of nonlinear ordinary differential equations. The resulting system of nonlinear ordinary differential equations are then solved by using the shooting method along with Adams-Moultan method. The numerical solution obtained for the velocity, temperature and concentration profiles has been presented through graphs for different choice of the physical parameters.

The article investigates the behaviour of the multiplication table of the ring \(\mathbb{Z}_n\). To count the number of 1s appear on the main diagonal of the multiplication table of \(\mathbb{Z}_n\), conclusively an explicit formula is induced for any \(n \geq 2\).

In this paper, we extend some estimates of the right hand side of a Hermite- Hadamard-Fejér type inequality for generalized convex functions whose derivatives absolute values are generalized convex via local fractional integrals.

This work is concerned with a comparative study of performances of meshfree (radial basis functions) and mesh-based (finite difference) schemes in terms of their accuracy and computational efficiency while solving multi-dimensional initial-boundary value problems governed by a nonlinear time-dependent reaction-diffusion Brusselator system. For computing the approximate solution of the Brusselator system, we use linearly implicit Crank-Nicolson (LICN) scheme, Peaceman-Rachford alternating direction implicit (ADI) scheme and exponential time differencing locally one dimensional (ETD-LOD) scheme as mesh-based schemes and multiquadric radial basis function (MQRBF) as a meshfree scheme. A few numerical results are reported.

In ring \(\mathbb{R}=\mathbb{Z}_{2}+u\mathbb{Z}_{2}+u^2\mathbb{Z}_{2}\) where \(u^3=0,\) using Lee weight and generalized Lee weight, some lower bound and upper bound on the covering radius of codes is given and also to find the covering radius for various repetition codes with respect to same and different length in \(\mathbb{R}.\)

There has been much debate about the role Vitamin C plays in the innate immune response, and if it has the potential to be used as a drug to combat conditions in which the immune system is compromised, from the common cold to cystic fibrosis. Here, the author creates a basic model of the innate response, capturing the dynamics among phagocytic cells, host cells, foreign virus/bacteria, and Vitamin C. Through mathematical simulations, the author concludes that Vitamin C can be used as a stand-alone drug to eradicate a viral/bacterial infection if given constant infusions. If this is not possible due to other side effects that may harm the patient, Vitamin C may be used in quick succession with another anti-bacterial/anti-viral medication to aid the patient. This, moreover, could help minimize the amount of side effects of the anti-bacterial/anti-viral drug and slow down bacterial evolution. Finally, the author modifies the system to simulate cases of renal failure, acute lung injury, liver damage, chronic granulomatous disease, and the Chédiak-Higashi syndrome, showing how Vitamin C can help individuals with these diseases.

In the 3-dimensional Euclidean space \(\mathbb{E}^{3}\) and Lorentzian-Minkowski space \(\mathbb{E}_{1}^{3},\) a translation and homothetical TH-surface is parameterized \(z(u,v)=A(f(u)+g(v))+Bf(u)g(v),\) where \(f\) and \(g\) are smooth functions and \(A\), \(B\) are non-zero real numbers. In this paper, we define TH-surfaces in the 3-dimensional Euclidean space \(\mathbb{E}^{3}\) and Lorentzian-Minkowski space \(\mathbb{E}_{1}^{3}\) and completely classify minimal or flat TH-surfaces.

Cervical cancer is a global threat with over half a million cases worldwide and over 200000 deaths annually. Sexual minority women are at risk for infection with human papillomavirus (HPV); the virus which causes cervical cancer, yet little is known about the prevalence of HPV infection. In this paper, the dynamics of HPV infection in the presence of vaccination among women which progresses to cervical cancer is investigated. The disease-free equilibrium state of the model is determined. Using the next generation method, the cancer reproduction number, \(R_0\), is computed in terms of the model parameters and used as a threshold value. The reproduction number is examined analytically for its sensitivity to the vaccination parameter having shown that it is locally and globally asymptotically stable for \(R_0<1\) and unstable for \(R_0>1\) at the disease free state. The centre manifold theorem is used to determine the stability of the endemic equilibrium and shown to exhibit a backward bifurcation phenomenon implying that cervical cancer due to HPV infection may persist in the population even if \(R_0<1\). Finally, numerical simulations are carried out to obtain analytical results. As prevalence estimates vary between sexual orientation dimensions, these findings help inform targeted HPV and cervical cancer prevention efforts.

The study of integral operators has always been important in the subjects of mathematics, physics, and in diverse areas of applied sciences. It has been challenging to discover and formulate new types of integral operators. The aim of this paper is to study and formulate an integral operator of a general nature. Under some suitable conditions the existence of a new integral operator is established. The boundedness of left and right sided integral operators is obtained and further boundedness of their sum is given. The investigated integral operators derive several known integrals and have interesting consequences for fractional calculus integral operators and conformable integrals. The presented results provide the boundedness of various fractional and conformable integral operators simultaneously.